Denosumab: A Potential Treatment Option for Aneurysmal Bone Cysts
Status:
Completed
Trial end date:
2017-12-31
Target enrollment:
Participant gender:
Summary
The efficacy of traditional therapeutic approaches for aneurysmal bone cysts (ABC), such as
surgery, embolization, sclerotherapy and radiotherapy, are often compromised for lesions in
axial skeletons and adolescents complicated with pathological fracture. Therefore, denosumab,
a new drug that has been successfully used in giant cell tumor of bone but has seldom used in
ABC, was used to treat ABC in this trial.