Overview

Dendritic Cell Immunotherapy Against Cancer Stem Cells in Glioblastoma Patients Receiving Standard Therapy

Status:
Recruiting
Trial end date:
2025-05-01
Target enrollment:
Participant gender:
Summary
Open, randomized study of a trivalent dendritic cell therapy compared to standard therapy in primary treated patients with IDH wild-type, MGMT-promotor methylated glioblastoma. The IMP is dendritic cells transfected with mRNA of survivin, hTERT og autologous tumor stem cells derived from tumorspheres.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Oslo University Hospital
Treatments:
Dacarbazine
Temozolomide
Vaccines