Overview

Delta-8-THC vs. Delta-9-THC on Simulated Driving Performance

Status:
COMPLETED
Trial end date:
2025-09-08
Target enrollment:
Participant gender:
Summary
Delta-8-THC is an isomer of delta-9-THC that has become widely available due to the legalization of hemp and its derivatives. Very little controlled research has been conducted with delta-8-THC and some research suggests it produces similar effects to delta-9-THC, albeit at lower potency. The present study will evaluate the dose effects of delta-8-THC, compared with delta-9-THC, on simulated driving performance, field sobriety tests, cognitive performance, and biomarkers of exposure to cannabinoids. The results will inform policy and education related to impairment due to acute delta-8-THC exposure via vaporization and oral ingestion.
Phase:
PHASE1
Details
Lead Sponsor:
Johns Hopkins University
Collaborator:
Substance Abuse and Mental Health Services Administration (SAMHSA)
Treatments:
delta-8-tetrahydrocannabinol
Dronabinol