Del Nido Versus HTK Cardioplegia in Adult Aortic Valve Replacement
Status:
ACTIVE_NOT_RECRUITING
Trial end date:
2024-09-24
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to compare del Nido and Bretschneider-HTK (HTK) cardioplegia solutions in patients undergoing elective aortic valve replacement. The main question it aims to answer is:
• Does the del Nido cardioplegia provide better cardioprotection and clinical outcomes than HTK cardioplegia? Participants will receive one of the investigated cardioplegia solutions according to the randomization.
Researchers will compare both groups in terms of cardioprotection (described as levels of CK-MB and hsTnI), in-hospital clinical outcomes, biochemical changes in coronary sinus blood and one-year follow-up.
Phase:
PHASE4
Details
Lead Sponsor:
Medical University of Gdansk
Treatments:
Bretschneider cardioplegic solution Del Nido cardioplegia solution