Dehydroepiandrosterone (DHEA) Treatment in Women and Men Experiencing Hypoactive Sexual Desire Disorder
Status:
Unknown status
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
Hypoactive Sexual Desire Disorder (HSDD) is a common syndrome characterized by low sexual
desire causing marked distress. The involvement of DHEA in sexual function is unknown,
however, DHEA treatment increased desire in depressed subjects. In the current research, we
will treat 45 women and men suffering from low sexual desire with DHEA or placebo for 6
weeks. The study's primary goal is to determine the effect of DHEA treatment on sexual
desire, and to find if there is a connection between levels of hormones and change in desire.
Outcome measures will include hormonal levels and psychological state. Our secondary goal is
to compare baseline hormones measures in individuals with low sexual desire to normal
controls. For that purpose we will measure the hormonal baseline levels among 20 normal
subjects.