Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery
Status:
Completed
Trial end date:
2019-02-06
Target enrollment:
Participant gender:
Summary
This is a two period cross-over study randomizing patients undergoing laparoscopic surgery
into 2 different groups: group 1 in which patients receive "deep neuromuscular blockade" in
the beginning portion of their laparoscopic surgery followed by a period of "moderate
blockade" and, group 2 in which patients receive "moderate neuromuscular blockade" in the
beginning portion of their laparoscopic surgery followed by a period of "deep blockade". The
deep neuromuscular block is defined as post tetanic count of 1 to 2 and the moderate
neuromuscular block is defined as 1-2 twitches. In all patients, sugammadex is used to
reverse the block at the end of surgery in order to obtain optimal extubating conditions.