Deep Neuromuscular Blockade During Robotic Radical Prostatectomy
Status:
Unknown status
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
Basic requirement for safe performance of the robotic intra-abdominal surgery is a calm and
clear surgical field after the introduction of a capnoperitoneum. That can be enabled by a
neuromuscular blockade. Provision of standard neuromuscular blockade is a compromise between
optimal surgical conditions (sufficiently deep block) and capability to antagonize the block
rapidly at the end of the surgery. With rocuronium, it is possible to maintain deep
neuromuscular blockade safely until the very end of the surgery, and unlike with spontaneous
recovery or reversal of the block with neostigmine, administration of sugammadex at the end
of the surgery will enable quick and consistent reversal of the block. Project is focused on
comparison of the parameters of deep and standard neuromuscular blockade - surgical
conditions (primary endpoint), quality of recovery and turnover time (secondary endpoints).
Phase:
Phase 4
Details
Lead Sponsor:
Palacky University
Collaborators:
Masaryk Hospital Usti nad Labem Masaryk Hospital, Usti nad Labem University Hospital Olomouc