Decitabine With or Without Valproic Acid in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Drugs used in chemotherapy, such as decitabine, work in different ways to stop the growth of
cancer cells, either by killing the cells or by stopping them from dividing. Valproic acid
may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
Giving decitabine together with valproic acid may be an effective treatment for non-Hodgkin's
lymphoma. This phase I trial is studying the side effects and best dose of decitabine and
valproic acid in treating patients with relapsed or refractory aggressive B-cell
non-Hodgkin's lymphoma.