Data Analyses for Ancillary WISE Femhrt Hormone Replacement Study
Status:
Completed
Trial end date:
2010-03-01
Target enrollment:
Participant gender:
Summary
The goal of the main trial was to evaluate the effect of low dose hormone replacement therapy
with 1 mg norethindrone/10mcg ethinyl estradiol in postmenopausal women with a history of
chest discomfort, myocardial ischemia and no obstructive CAD. For the purposes of this study
as a core lab coordinating center, the investigators will be performing P31 MRS core lab
analyses; hormone core lab analyses; lipid core lab analyses; glucose, insulin and HOMA core
lab analyses; exercise stress test/Holter monitor core lab analyses; brachial artery
reactivity test core lab analyses; full study data analyses for manuscript preparation and
the writing and submission and publication of manuscript.
The main trial duration: December 1999 - May 2003.
The ancillary data analysis project duration: April 2006 - March 2010.
Phase:
N/A
Details
Lead Sponsor:
Cedars-Sinai Medical Center
Collaborators:
Allegheny University Johns Hopkins University Parke-Davis University of Alabama at Birmingham University of Florida University of Pittsburgh