Overview

Dalteparin, Lenalidomide, and Low-Dose Dexamethasone in Treating Patients With Previously Untreated Multiple Myeloma

Status:
Terminated
Trial end date:
2017-10-31
Target enrollment:
Participant gender:
Summary
This randomized pilot phase II trial studies how well giving dalteparin, lenalidomide, and low-dose dexamethasone together works in treating patients with previously untreated multiple myeloma. Anticoagulants, such as dalteparin, may help prevent blood clots from forming in patients being treated with lenalidomide and dexamethasone for multiple myeloma. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Drugs used in chemotherapy, such as dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving dalteparin, lenalidomide, and dexamethasone together may be an effective treatment for multiple myeloma
Phase:
Phase 2
Details
Lead Sponsor:
University of Southern California
Collaborators:
Celgene Corporation
National Cancer Institute (NCI)
Treatments:
BB 1101
Dalteparin
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Heparin, Low-Molecular-Weight
Lenalidomide
Thalidomide
Tinzaparin