DHA and Vitamin D in Children With Biopsy-proven NAFLD
Status:
Completed
Trial end date:
2015-09-01
Target enrollment:
Participant gender:
Summary
Non-alcoholic fatty liver disease (NAFLD) has reached epidemic proportions and is rapidly
becoming the one of most common causes of chronic liver disease in children. The pathogenesis
of NAFLD is generally considered the result of a series of liver injuries, commonly referred
as "multi-hit" hypothesis. Several studies suggest that inflammatory pathways and oxidative
stress could be responsible of disease progression.
The purpose of this interventional study is to evaluate the efficacy and tolerability of
docosahexaenoic acid (DHA) and Vitamin D in children and adolescents with biopsy-proven
nonalcoholic fatty liver disease (NAFLD).