Overview

DDI Study of Orelabrutinib

Status:
Active, not recruiting
Trial end date:
2022-05-10
Target enrollment:
Participant gender:
Summary
This is a phase I, single-center, open-label, fixed-sequence clinical study. The primary objective was to evaluate the effects of multiple administrations of rifampin or itraconazole on the pharmacokinetic characteristics of a single administration of orelabrutinib tablets in healthy Chinese subjects. The secondary objective was to evaluate the safety and tolerability of rifampicin or itraconazole combined with orelabrutinib tablets in healthy Chinese subjects.
Phase:
Phase 1
Details
Lead Sponsor:
Beijing InnoCare Pharma Tech Co., Ltd.
Treatments:
Itraconazole
Rifampin