DASH After TBI Study: Decreasing Adrenergic or Sympathetic Hyperactivity After Traumatic Brain Injury
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
The investigators intend to determine the effect of adrenergic blockade on 1) short-term
physiology, behavior, and cognition and 2) long-term neuropsychological outcomes after severe
Traumatic Brain Injury (TBI).
The primary hypothesis is that adrenergic blockade after severe TBI will be associated with
increased ventilator-free days.
Phase:
Phase 2
Details
Lead Sponsor:
Vanderbilt University
Collaborators:
Eastern Association for the Surgery of Trauma (EAST) Vanderbilt Institute for Clinical and Translational Research (CTSA)