D-cycloserine and Virtual Reality Exposure to Treat Iraq War Veterans With PTSD

• Status: Completed
• Trial end date: 2014-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will determine whether a combination of virtual reality exposure therapy and D-cycloserine will reduce post-traumatic stress disorder symptoms in Iraq war veterans.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Emory University
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Alprazolam; Cycloserine

Criteria

Inclusion Criteria:

• Meets DSM-IV criteria for PTSD due to Iraq military trauma

• Speaks English

• Healthy overall

Exclusion Criteria:

• History of mania, schizophrenia, or other psychoses

• Suicidal

• Current alcohol or drug dependence

• Medication free within 2 weeks of study entry for any medication that has been taken less than daily for the past month and medicine free within 4 weeks of study entry for any anxiolytic medication that has been taken daily for the last month or more

• Pregnant

• Special medical conditions, such as kidney insufficiency, chronic diseases, or history of significant head injury

• Stabilized on potentially data obscuring medication such as glucocorticoids