D-CTAG in the Treatment of Newly Diagnosed Acute Myeloid Leukemia in Elderly Patients
Status:
Recruiting
Trial end date:
2024-12-30
Target enrollment:
Participant gender:
Summary
With the aging of society, the incidence of elderly leukemia in China has been increasing
year by year. The elderly patients with Acute Leukemia have poor basal state, and there are
many important organ diseases such as heart, liver and kidney. The incidence of infection and
hemorrhage is high in elderly patients after chemotherapy. These characteristics make the
treatment of elderly leukemia difficult. So we propose a new treatment plan by using the
therapy that rhTPO may promote the leukemia cells into the division cycle.We use the
synergistic effect of G-CSF and rhTPO to promote leukemia cells into the division cycle,
thereby the cells can be killed by cytotoxic drugs. At the same time, G-CSF and rhTPO are
used to promote the growth of granulocytes and platelets, therefore the side effects of
treatment of elderly leukemia can be alleviated. We provide a safe and effective chemotherapy
for elderly leukemia patients, so that more elderly patients receive chemotherapy,which has
important practical significance.