Cytoscopic Antibiotic Irrigant to Reduce Postoperative Urinary Tract Infection

• Status: Completed
• Trial end date: 2020-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

Postoperative urinary tract infections (UTIs) affect 20-30% of patients undergoing elective gynecologic surgery and have a significant socioeconomic impact and cost. Preoperative antibiotics, sterile operating techniques, postoperative antibiotic and non-antibiotic medical therapies have been utilized to attempt to decrease this rate with little improvement. Utilization of an intraoperative antibiotic cystoscopic irrigant may decrease postoperative UTIs. The investigators have designed a prospective randomized controlled study to evaluate the effectiveness of an antibiotic cystoscopic fluid in preventing postoperative urinary tract infections in women undergoing elective pelvic floor surgery with cystoscopy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: MetroHealth Medical Center
• Treatments: Anti-Bacterial Agents; Bacitracin; Bacitracin zinc, neomycin sulfate, polymyxin B, drug combination; Neomycin; Polymyxin B

Criteria

Inclusion Criteria:

• Adult women at least 18 years of age

• Elective Female Pelvic Medicine and Reconstructive Surgery or Gynecologic Minimally Invasive surgeries including hysterectomy, suburethral sling, and pelvic organ prolapse repair that require cystoscopy.

Exclusion Criteria:

• Surgeries that include: intradetrusor Botox, vaginal mesh excision, and fistula repair

• Pregnancy

• History of nephrolithiasis

• Allergy to study medications

• Congenital urogenital anomaly

• Neurogenic bladder