Custodiol Versus Blood Cardioplegaia in Paediatric Cardiac Surgery
Status:
Unknown status
Trial end date:
2020-01-20
Target enrollment:
Participant gender:
Summary
Cardioplegic arrest is an essential part of cardiac surgery which aims to allow myocardial
preservation and minimise myocardial swelling ,while providing a motionless and bloodless
field ,.Blood cardioplegia has proven its efficacy for several decades and surgeons are still
preferring to use it for myocardial protection of paediatric cardiac surgery ,although it is
thought to be more time consuming since it is given with interrupted doses, . Even when
advancement has came along the field of myocardial protection and cardioplegia solutions with
the introduction of Bretschneider Histidine-Tryptophan-Ketoglutarate solution ,custodiol ,in
1970 ,which is given as a single dose and believed to be convenient, simple to deliver , and
less time consuming . Many Surgeons haven't change their practice possibly due to paucity of
studies comparing cardioplegia solutions in paediatric cardiac surgery and conflicting
reports regarding the superiority of different cardioplegia solution.The investigators aim to
provide evidence that will help paediatric cardiac surgeons to choose the optimal solution
for their practice .
Phase:
Phase 2
Details
Lead Sponsor:
King Faisal Specialist Hospital & Research Centre, Jeddah