Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults With ADPKD
Status:
Completed
Trial end date:
2021-02-01
Target enrollment:
Participant gender:
Summary
The proposed research will determine the effectiveness of curcumin for improving the health
and function of arteries in children and young adults with autosomal dominant polycystic
kidney disease (ADPKD). The study also will provide insight into how curcumin improves artery
health by determining the physiological mechanisms (biological reasons) involved and offer
exploratory evidence if curcumin can slow kidney growth. This will be done by comparing these
measurements in children and young adults who are randomized to receive either curcumin or
placebo for 1 year.