Crystalloids or Colloids for Goal-directed Fluid Therapy With Closed-loop Assistance in Major Surgery
Status:
Completed
Trial end date:
2017-12-21
Target enrollment:
Participant gender:
Summary
Study goal: This study will examine whether there is a significant difference in
postoperative outcomes between GDFT using a colloid solution versus a crystalloid solution.
Hypothesis: Perioperative fluid optimization through the use of a closed-loop assistance with
a balanced starch solution (volulyte®) will be associated with a decrease in postoperative
complications compared to the same approach using a balanced crystalloid solution
(Plasmalyte®).
Objective: To establish which kind of intravenous fluid used for goal directed therapy with
closed-loop assistance will reduce the number of postoperative complications (evaluation made
by the POMS score).