Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis
Status:
Recruiting
Trial end date:
2022-06-01
Target enrollment:
Participant gender:
Summary
Multicenter, prospective, phase 3 randomized non-blinded interventional trial of fluid
treatment strategies in the first 24 hours for patients with sepsis-induced hypotension. The
aim of the study is to determine the impact of a restrictive fluids strategy (vasopressors
first followed by rescue fluids) as compared to a liberal fluid strategy (fluids first
followed by rescue vasopressors) on 90-day in-hospital mortality in patients with
sepsis-induced hypotension.