Overview

Cryoablation Combined With Lenvatinib Plus Tislelizumab Compared With FOLFOX in Patients With Advanced Intrahepatic Cholangiocarcinoma (CASTLE-ZS-01)

Status:
RECRUITING

Trial end date:
2028-03-15

Target enrollment:

Participant gender:

Summary

This study will evaluate the efficacy and safety of cryoablation combined with lenvatinib plus Tislelizumab compared with FOLFOX in patients with advanced Intrahepatic Cholangiocarcinoma (ICC) who have progressed after first-line treatment.

Phase:

PHASE2

Details

Lead Sponsor:

Fudan University

Treatments:

Cryosurgery
Fluorouracil
Folfox protocol
lenvatinib
Leucovorin
Oxaliplatin
tislelizumab