Cross-linking of Corneal Collagen (CXL) With Ultraviolet-A in Asymmetric Corneas
Status:
Terminated
Trial end date:
2017-02-03
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the efficacy of ultraviolet-A (UVA)-induced
cross-linking of corneal collagen (CXL) as a method to increase the biomechanical and
biochemical stability of the cornea by inducing additional cross-links within or between
collagen fibers using UVA light and the photo- mediator riboflavin. The purpose of this study
is to generate data for presentation at medical meetings and for peer-review publication. The
data generated by this study will not be submitted to the FDA to support commercialization of
these riboflavin drops.