Cox-2 Inhibition in Radiation-induced Oral Mucositis
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
Oral mucositis refers to ulcerative lesions of the oral mucosa that occur due to radiation
therapy given for treatment of head and neck cancer. These lesions are painful, compromise
nutrition and quality of life and may necessitate interruptions in radiation therapy, thus
adversely affecting cancer therapy outcomes. This study examined the use of an
anti-inflammatory medicine to reduce pain and severity of oral mucositis.
Phase:
Phase 2
Details
Lead Sponsor:
UConn Health
Collaborators:
National Institute of Dental and Craniofacial Research (NIDCR) Pfizer