Could Early Atorvastatin Offer Anti Inflammatory Effects Upon Brain in Traumatic Head Injury?
Status:
Recruiting
Trial end date:
2022-04-01
Target enrollment:
Participant gender:
Summary
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, known as statins, are widely used
to reduce levels of low-density lipoprotein-cholesterol. As lipid-lowering drugs, statins
exert neuroprotective effects on ischemic stroke. this study will investigate whether the
protective effect of statins is mediated by their ability to impact inflammation and oxygen
free radical levels in cerebral ischemia/reperfusion injury.
Could Statins affect the neuroinflamation which occurs after traumatic brain injury?