Approximately 50% of patients admitted for severe AH will have spontaneous improvement of
liver function before initiation of therapy (ie decrease in mDF between hospital admission
and initiation of steroids). These patients have a better prognosis than patients without
spontaneous improvement of liver function. It has never been demonstrated that
corticosteroids improve survival in severe AH patients with spontaneous improvement of liver
function. Our hypothesis is that severe AH patients with spontaneous improvement of liver
function represent a group who could most benefit from steroids
Phase:
N/A
Details
Lead Sponsor:
Erasme University Hospital
Collaborator:
Belgian Association for the Study of the Liver (BASL)