Overview

Corticosteroid Therapy for Glucocorticoid Insufficiency Related to Traumatic Brain Injury

Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
Traumatic brained injured (TBI) patients frequently suffered from glucocorticoid insufficiency that is associated with a raise in the rate of pneumonia. In a placebo-controlled, multi-center, double-blinded trial, treatment of glucocorticoid insufficiency (hydrocortisone associated with fludrocortisone) will be assessed for prevention of post trauma pneumonia in a population of severe TBI patients.
Phase:
Phase 3
Details
Lead Sponsor:
Nantes University Hospital
Collaborator:
Société Française d'Anesthésie et de Réanimation
Treatments:
Cortisol succinate
Fludrocortisone
Glucocorticoids
Hydrocortisone
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate