Corticosteroid Pulse After Ablation

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Radiofrequency ablation is an effective treatment for atrial fibrillation. However, about 20% of the time the atrial fibrillation recurs. Steroids given after the ablation may decrease inflammation caused by the ablation and thus improve healing and decrease the chance of recurrence of atrial fibrillation.

In this study patients will be randomized to receive intravenous steroids or not immediately following the ablation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Minneapolis Heart Institute Foundation
• Collaborators: Abbott Medical Devices; St. Jude Medical
• Treatments: Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• Age ≥ 18

• Drug refractory, symptomatic paroxysmal atrial fibrillation

Exclusion Criteria:

• Contraindication to solumedrol

• Persistent or permanent Atrial Fibrillation

• Previous history of radiofrequency ablation for atrial fibrillation