Corticosteroid Intra-articular Injection in Hands Osteoarthritis
Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
Objective - to evaluate the effectiveness and tolerance of intra-articular injections (IAI)
of hexacetonide triamcinolone (HT) for the treatment of osteoarthritis (OA) in
interphalangeal joints.
Design:randomized, controlled, double-blinded study Materials and methods: sixty patients
were randomized into: the TH / lidocaine (LD) group (n=30) who underwent IAI at the most
symptomatic interphalangeal joint with HT (20mg/ml) and LD 2% or the LD group (n=30) who
received IAI with just LD. Patients were assessed at baseline, 1, 4, 8 and 12 weeks by a
blinded observer. The following parameters regarding the affected joint were assessed: pain
at rest (VASr); pain at movement (VASm); pain (VAS) during the 48 hours after the procedure;
swelling (VASs); goniometry; grip and pinch strength; hand function; treatment improvement;
daily requirement of paracetamol and incidence and types of local side effects after the
procedure.