Cortical Neuroplasticity by Muscle Pain of Pain-induced Plasticity

• Status: Completed
• Trial end date: 2018-02-28
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate the sensory-motor cortical excitability response to delayed onset muscle soreness (DOMS) on Extensor Carpi Radialis (ECR) muscle during muscle hyperalgesia provoked by nerve growth factor (NGF).

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Aalborg University
• Treatments: Mitogens

Criteria

Inclusion Criteria:

• Healthy men and women

• Speak and understand English.

Exclusion Criteria:Pregnancy

• Drug addiction defined as the use of cannabis, opioids or other drugs

• Previous neurologic, musculoskeletal or mental illnesses

• Lack of ability to cooperate

• History of chronic pain or current acute pain

• Previous experience with rTMS

• Contraindications to rTMS application (history of epilepsy, metal in the head or jaw etc.).

• Failure to pass the "TASS questionnaire" (TASS = Transcranial Magnetic Stimulation Adult Safety Screen)