Overview

Correlation Between Acute Analgesia and Long-Term Function Following Ankle Injuries

Status:
Unknown status
Trial end date:
2019-12-01
Target enrollment:
0
Participant gender:
All
Summary
In this 4-arm pragmatic randomized control trial, the investigators hope to decipher whether the use of non-opioid analgesics (naproxen, celecoxib, acetaminophen) in addition to standardized physiotherapy during the acute phase of grade I-II ankle injuries will result in functional differences compared to standardized physiotherapy alone
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Canadian Department of National Defense
Treatments:
Acetaminophen
Celecoxib
Naproxen
Criteria
Inclusion Criteria:

- Acquired acute ankle injury (injured less than 48 hours ago);

- Clinical diagnosis of a Grade I or II ankle sprain

- Is eligible to receive comprehensive medical care from Garrison Petawawa

Exclusion Criteria:

- Diagnosis of ankle fracture or ligament rupture

- Has planned release from the Canadian Armed Forces within one year;

- Documented restrictions on military duties

- Has known intolerance or documented adverse reaction to acetaminophen or naproxen or
celecoxib

- Documented history of liver or kidney problems

- pregnant or breastfeeding