Overview

Correlate BRCA1 Protein Expression With Response to DNA Damaging Chemotherapy

Status:
Active, not recruiting
Trial end date:
2022-08-01
Target enrollment:
Participant gender:
Summary
Primary Objective: To evaluate if low BRCA1 protein expression has a preferential effect on response when metastatic breast cancer patients are treated with DNA damaging chemotherapy agent, compared to historical controls Secondary Objective: To evaluate if low BRCA1 protein expression has a preferential effect on tumor progression when metastatic breast cancer patients are treated with DNA damaging chemotherapy agent, compared to historical controls
Phase:
Phase 2
Details
Lead Sponsor:
University of Arizona
Treatments:
Doxorubicin
Liposomal doxorubicin