Corneal Collagen Cross-Linking for Ectasia (CXL)

• Status: Completed
• Trial end date: 2011-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Prospective, randomized multicenter study to determine the safety and effectiveness of performing corneal collagen cross-linking (CXL) using riboflavin and UVA light in eyes with ectasia after refractive surgery.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Avedro, Inc.; Glaukos Corporation
• Treatments: Ophthalmic Solutions; Pharmaceutical Solutions; Riboflavin

Criteria

Inclusion Criteria:

• Diagnosis of ectasia after refractive surgery

• Documented ectasia on Pentacam or topography map

• BSCVA worse than 20/20

• Must complete all study visits

Exclusion Criteria:

• History of delayed wound healing

• History of corneal melt or corneal dystrophy