Corifollitropin Alfa Versus Daily rFSH in the Controlled Ovarian Stimulation of Poor Responders
Status:
Terminated
Trial end date:
2015-11-01
Target enrollment:
Participant gender:
Summary
A randomised, crossover, multicentre, national, clinical trial comparing the efficacy of
corifollitropin alfa versus daily recombinant FSH and HMG in the controlled ovarian
stimulation of women with a poor ovarian response undergoing IVF treatments. The main
objective of this study is comparing the number of oocytes obtained after the follicle
puncture when using each of these two stimulation protocols. Only poor responders according
to the Bologna criteria will be recruited for this trial. All participants will undergo two
stimulation cycles to obtain and accumulate oocytes by vitrification. One of the cycles will
be done with the corifollitropin alfa protocol and the other with daily rFSH and HMG, the
order of application of these protocols will be randomised (crossover clinical trial) in each
patient.
Phase:
Phase 4
Details
Lead Sponsor:
IVI Sevilla
Collaborators:
Instituto Valenciano de Infertilidad, IVI VALENCIA IVI Barcelona IVI Madrid