Corifollitropin Alfa Compared to Daily rFSH in Poor Responders Undergoing ICSI
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Corifollitropin alfa has been shown to result in significantly more oocytes compared to daily
recombinant follicle stimulating hormone (recFSH) (Devroey et al., 2009), probably due to the
higher circulating FSH activity during the first days of stimulation. For this reason, the
use of corifollitropin alfa might be beneficial in poor responders in whom the number of
oocytes retrieved is crucial for success.
The purpose of this study is to evaluate the effectiveness of corifollitropin alfa treatment
compared to daily recFSH in terms of the number of oocytes retrieved in a defined population
of poor responder patients undergoing intracytoplasmic sperm injection (ICSI) using
gonadotrophin releasing hormone (GnRH) antagonists.