Conversion of Seddon III Nerve Injury to Seddon I/II Nerve Injury

• Status: Recruiting
• Trial end date: 2024-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the safety and efficacy of PEG 3350 for use in nerve repair.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: WellSpan Health
• Collaborator: Neuraptive Therapeutics Inc.

Criteria

• Isolated nerve transections of the digits, forearm, wrist, and palm will be included.

• Class III nerve injury (Sunderland's 4th or 5th degree injury)

• Nerve injuries that can be prepared using minimal or acceptable tension (according to surgeon discretion).

• Pregnant and breastfeeding women cannot participate because of possible unknown and unpredictable risks to the unborn child.

• Injuries beyond 24 hours will be excluded