Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy

• Status: Recruiting
• Trial end date: 2025-03-01
• Target enrollment: 0
• Participant gender: All

Summary

• Hypoparathyroidism is the most common complication after a total thyroidectomy surgery. It becomes permanent after 6 months.

• Untreated permanent hypoparathyroidism is a source of numerous complications in general and therefore requires lifelong replacement therapy resulting in a significant deterioration in quality of life.

• The intraoperative use of indocyanine green (ICG) angiography has recently been described as a reliable means of detecting parathyroidism and predicting the risk of postoperative hypoparathyroidism.

• This use could prove to be a way to preserve parathyroid in vivo and thus reduce post-operative hypoparathyroidism rates.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Brest

Criteria

Inclusion Criteria:

• Patient having to undergo a total thyroidectomy

• Signed consent

• Patient beneficiary of a social security regimen

Exclusion Criteria:

• Minor patient under 18 years old

• Major patient protected by law or unable to give informed consent

• Pregnant or breastfeeding woman

• Thyroidectomy totalization

• History of thyroid or parathyroid surgery

• Participation refusal

• Known allergy to ICG

• Woman of child-bearing age not using adequate method of contraception