Overview

Contrast Enhanced Ultrasound for Evaluation of Reflux Nephropathy

Status:
Completed
Trial end date:
2016-11-01
Target enrollment:
0
Participant gender:
All
Summary
The study will be evaluating the efficacy and safety of a contrast drug in pediatric renal ultrasound.
Phase:
Phase 2
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Tennessee
Criteria
Inclusion Criteria:

- Informed consent

- Age more than or equal to 8 years

- Patient with history of urinary tract infection (UTI) and history of Voiding
Cystourethrogram (VCUG) for vesicoureteral reflux

- Candidate for Dimercaptosuccinic acid (DMSA) scan or scan for renal scar

- Demonstration of renal scarring by DMSA scan or renal ultrasound without contrast

Includes healthy volunteers

Exclusion Criteria:

- Age less than 8years

- Allergy to contrast or related products

- Cardiac shunt/ congenital heart anomalies

- Abnormal baseline ECG

- Open heart surgery

- Evidence of retinopathy

- Patient in intensive care

- Unable to comply with study requirement

- History of emphysema

- Unable to maintain oxygen saturation of 92% on at room air

- Pregnancy and lactation