Continuous Thoracic Paravertebral Analgesia for Video-assisted Thoracoscopic Surgery

• Status: Terminated
• Trial end date: 2017-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to assess:

• The impact of continuous thoracic paravertebral nerve blockade compared to intercostal nerve blockade on the intensity of postoperative pain following VATS in subjects having a Patient Controlled Analgesia (PCA) device as their primary analgesic modality.

• The impact of continuous thoracic paravertebral analgesia on length of stay, opioid intake, respiratory function, incidence of side-effects and postoperative complications.

The basic hypothesis of this study is that continuous thoracic paravertebral nerve blockade will provide superior postoperative analgesia following VATS when compared to intercostal nerve blockade in patients having a PCA device as their primary analgesic modality. Superior quality of analgesia should contribute to preserve pulmonary function, reduce opioid intake and related side-effects and shorten the hospital stay.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• Patients scheduled for an elective or emergency VATS surgery (lobectomy or bilobectomy)

• Patients eligible for fast-track surgery

• American Society of Anesthesiologists (ASA) physical status from 1 to 3

Exclusion Criteria:

• Contraindication to paravertebral nerve blockade

• Severe hepatic insufficiency

• Renal insufficiency

• Known allergy to local anesthetics, morphine or hydromorphone

• Contraindication to acetaminophen or non-steroidal anti-inflammatory drugs (NSAID)

• Inability to understand a verbal numeric pain scale despite previous instruction

• Inability to understand the instructions and precautions related to the use of a portable infusion pump or absence of a resource person or natural caregiver at home

• Preexisting pain at the site where the surgical incision will be made

• Current use of opioids, anticonvulsants or tricyclic antidepressants

• Recent history of drug or opioid abuse