Continuous Oral Contraceptive Treatment in Premenstrual Dysphoric Disorder (PMDD)
Status:
Completed
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare a low dose oral contraceptive (OC) given continuously
(every day for three months) with the same low dose oral contraceptive given in an
interrupted regimen (one week of inactive placebo pills each month) and with continuous
placebo (inactive placebo given every day for three months). The primary hypothesis is that
continuous OC will be significantly more effective in reducing premenstrual symptoms compared
with either the interrupted OC or continuous placebo.
Phase:
Phase 4
Details
Lead Sponsor:
University of North Carolina, Chapel Hill
Collaborator:
National Institute of Mental Health (NIMH)
Treatments:
Contraceptive Agents Contraceptives, Oral Drospirenone and ethinyl estradiol combination