Continuous NMB in PCAS

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The main purpose of this study is to test the hypothesis that continuous NMB could improve outcome in cardiac arrest patients treated with therapeutic hypothermia.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chun Song Youn
• Collaborators: Asan Medical Center; Chonnam National University Hospital; Hanil General Hospital; Hanyang University Guri Hospitall; The Catholic University of Korea; Uijeongbu St. Mary's Hospital; Ulsan Universty Hospital
• Treatments: Neuromuscular Blocking Agents; Rocuronium

Criteria

Inclusion Criteria:

1. Adult (older than 19)

2. OHCA with sustained ROSC

3. Comatose (i.e., not following commands) following ROSC

4. Undergoing targeted temperature management (TTM)

5. Time of enrollment ≤ 6hrs from ROSC

Exclusion Criteria:

1. Pre-existing dementia, brain injury, or dependence on others for ADLs (CPC > 3)

2. Traumatic etiology for cardiac arrest

3. Protected population (pregnant, prisoner)