Overview

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Status:
Unknown status
Trial end date:
2019-02-01
Target enrollment:
Participant gender:
Summary
The objectives of this study are to explore different dosing levels and schedules of entinostat in combination with pembrolizumab in patients with advanced solid tumors, in terms of safety, tolerability, pharmacokinetics (PK), impact on immune correlatives, and efficacy
Phase:
Phase 1
Details
Lead Sponsor:
Syndax Pharmaceuticals
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Entinostat
Histone Deacetylase Inhibitors
Pembrolizumab