Concurrent Chemoradiotherapy With Weekly Cisplatin Versus Concurrent Chemoradiotherapy With Weekly Cisplatin and Paclitaxel in Locally Advanced Carcinoma Cervix

• Status: Unknown status
• Trial end date: 2013-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to check whether addition of paclitaxel to cisplatin and radiation therapy will improve the outcome in locally advanced carcinoma cervix.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Indira Gandhi Medical College; Indira Gandhi Medical College, Shimla
• Treatments: Albumin-Bound Paclitaxel; Cisplatin; Paclitaxel

Criteria

Inclusion Criteria:

• histologically proven carcinoma cervix

• age 18 years to 65 years

• stage IIA, IIB, IIIA & IIIB according to FIGO 2009

Exclusion Criteria:

• age > 65 years and < 18 years

• stage IA, IB, IVA & IVB

• Histology other than squamous cell, adenocarcinoma or adenosquamous carcinoma

• history of prior pelvic surgery for cancer, prior pelvic radiotherapy or prior chemotherapy.

• deranged renal function test and liver function test

• KPS >= 60

• distant metastasis