Concomitant, Sequential, and Standard Triple Therapy for H. Pylori Infection
Status:
Completed
Trial end date:
2013-10-01
Target enrollment:
Participant gender:
Summary
To simultaneously compare the efficacies of 7-day triple, 10-day sequential and 7-day
quadruple therapies for H. pylori infection in Taiwan. Consecutive H. pylori-infected
patients were randomly assigned to a 7-day standard triple therapy (pantoprazole,
clarithromycin, and amoxicillin for 7 days), a 10-day sequential therapy (pantoprazole and
amoxicillin for 5 days, followed by pantoprazole, clarithromycin and metronidazole for a
further 5 days) or a 7-day quadruple therapy (pantoprazole, clarithromycin, amoxicillin and
metronidazole for 7 days). The end point is to evaluate the effectiveness of Helicobacter
pylori eradication rates between three groups.