Concentration Effect of Local Anesthetics on Femoral Nerve Block Efficiency

• Status: Completed
• Trial end date: 2019-02-15
• Target enrollment: 0
• Participant gender: All

Summary

US-guided femoral nerve block is used effectively in post-operative pain management in the surgical treatment of the lower extremity. However, the volume and concentration of the local anesthetic drug to be administered remains controversial. In this prospective, randomized, double-blinded study, patients who underwent unilateral primary total knee arthroplasty and successfully performed spinal anesthesia with standard method and dosage, will be selected for US-guided femoral nerve block after the operation. Patients will be divided into three groups with simple randomization. The First group will be determined as the control group (GCont) and only dressing will be applied to the patients. For second group(G125), 0,125% 20 ml local anesthetic and for the third group (G25), 0,25% 10 ml local anesthetic will be administered to the femoral nerve without changing the drug dose (25 mg bupivacaine). Whether there is a difference between post-op analgesia durations, motor block formation, mobilization time and 90° flexion time between the groups will be investigated.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bozyaka Training and Research Hospital
• Treatments: Bupivacaine; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Patients who are scheduled for primary unilateral total knee arthroplasty under spinal anesthesia

• Patients who has informed consent for study

Exclusion Criteria:

• Patient's refusal to participate

• Patients under 18 years of age

• Patients who are undergoing surgery with an anesthesia technique other than spinal anesthesia for any reason (general anesthesia, laryngeal mask application, etc.)

• Patients with known local anesthetic allergy

• Patients with Body mass index > 35

• Patients diagnosed sepsis and bacteriemia,

• Skin infection at the injection site,

• History of coagulopathy or anticoagulant therapy

• Patients with uncontrolled diabetes ,

• Uncoordinated patients,

• Psychological and emotional lability,

• Surgical intervention longer than 3 hours.

• Patients with pre-operative limitation of movement