Comprehensive Oral Intervention in Patients With AMI

• Status: Unknown status
• Trial end date: 2021-03-31
• Target enrollment: 0
• Participant gender: All

Summary

The investigators performed a randomized controlled trial with investigator-masked design enrolling subjects with acute myocardial infarction.

The purpose of this study is to find a treatment strategy to reduce the risk of recurrence of myocardial infarction through oral hygiene improvement.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Bundang Hospital
• Collaborator: National Research Foundation of Korea
• Treatments: Platelet Aggregation Inhibitors

Criteria

Inclusion Criteria:

• Adults over 18

• Patients diagnosed with type 1 or 2 MI according to the Fourth Universal Definition of Myocardial Infarction (2018) criteria

• Patients with baseline hsCRP (high-sensitivity C-reactive protein) elevated above 1.0 mg / dL

Exclusion Criteria:

1. clinical exclusion criteria

• Inability to provide informed consent

• Patients who are predicted to have low compliance

• Those whose life expectancy is less than 3 months due to cardiovascular disease or other reasons

• Those who are considered to be too poor condition to perform dental treatment or have a high risk of bleeding

• Those who need active dental treatment such as extraction

• Patients suspected of having active infection

• Those who are taking long-term systemic antibiotics or receiving immunosuppressive treatment

2. periodontal exclusion criteria

• Fully edentulous (Except for fixed implant restorations)

• If more than 15 teeth and implants do not exist

• If the last dental visit experience is less than 6 months

• If periodontal treatment is not possible by the researcher