Overview

Comprehensive Ambulatory Antibiotics for the Treatment of Congenital Syphilis

Status:
NOT_YET_RECRUITING
Trial end date:
2027-06-30
Target enrollment:
Participant gender:
Summary
CARES-1 is a randomised, open-label, phase II pharmacokinetic (PK) and safety study of ambulatory antibiotics for the treatment of neonates with "all-risk" asymptomatic congenital syphilis.
Phase:
PHASE2
Details
Lead Sponsor:
London School of Hygiene and Tropical Medicine
Collaborators:
Malawi Liverpool Wellcome Programme
MRC CTU at UCL
Murdoch Childrens Research Institute
PHPT/AMS Laboratory, Faculty of Associated Medical Sciences, Chiang Mai University
University College Dublin
University of Stellenbosch
University of Sydney
Treatments:
Amoxicillin
Linezolid
Penicillin G