Comparison the Effects of Dexamethasone and Loteprednol on Epithelial Healing
Status:
Completed
Trial end date:
2013-09-01
Target enrollment:
Participant gender:
Summary
Corticosteroid has been used for the treatment after phototherapeutic keratectomy (PRK).
Dexamethasone, a potent steroid can retard the corneal epithelial healing rate and has
numerous serious complications, especially glaucoma. Loteprednol, a new generation of
corticosteroid has less potency than dexamethasone and was proposed to has less side effect
regarding intraocular pressure (IOP) elevation. Therefore, Investigators would like to
compare the effect of dexamethasone and loteprednol on corneal epithelial healing rate after
PRK and risk of glaucoma.