Comparison on Efficacy and Safety of Three Inpatient Insulin Therapy in Type2 DM
Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
Purpose: To compare efficacy and safety of traditional sliding scale insulin (SSI) versus
modified 70/30 insulin versus modified basal plus supplemental scale /bolus insulin regimens
for glycemic control in hospitalized diabetic patients with diabetes.
Methods: In a prospective trial, patients with diabetes will be randomized to receive either
traditional hospital SSI , or twice daily 70/30 insulin plus supplemental lunchtime insulin
for BG ≥ 150 mg/dL or once every night glargine plus three times prandial glulisine for BG ≥
150 mg/dL . 70/30 insulin and glargine will be started respectively at 0.4 and 0.2 U/kg/day
for BG ≤ 200 mg/dL or 0.5 and 0.3 U/kg/day for BG above 200 mg/dL.