Comparison of the Therapeutic Effects of VR With Zoladex and VR in the Treatment of Cesarean Section Scar Defect

• Status: Not yet recruiting
• Trial end date: 2025-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

Zoladex will be used to postpone period after vaginal repair for Cesarean Section Scar Defect（CSD） patients with adenomyosis which will be compared with CSD patients with adenomyosis who receive transvaginal surgery without Zoladex, our group will assess whether delayed period improving the CSD prognosis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
• Treatments: Goserelin

Criteria

Inclusion Criteria:

1. Clearly diagnosed with CSD complicated with adenomyosis

2. Experiencing clinical features of abnormal uterine bleeding, prolonged menstrual flow (the duration of menstruation is more than 10 days).

3. The thickness of the remaining muscular layer of CSD was less than 3 mm.

4. Normal range of blood sugar and insulin

5. No serious medical problems (important viscera function in the normal range).

6. uterine fibroids no more than 5cm

7. Sign the informed consent.

Exclusion Criteria:

1. Indefinite diagnosis.

2. Malignant tumors.

3. With severe medical problems (severe liver disease, kidney disease, respiratory diseases, heart disease or uncontrolled diabetes, epilepsy, etc., dysfunction of important organs).

4. Pregnant.

5. Mental diseases.

6. Allergy to the any ingredients of Zoladex

7. Unwilling to comply with the research plan.