Comparison of the Manually Controlled Propofol Infusion and Target Controlled Infusion in Children
Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
Patients 1 to 8 years of age, American Society of Anesthesiologist score 1 and 2, planned for
elective, one day surgery: inguinal hernia repair, hydrocele surgery, testis retention
surgery, varicocele and phimosis surgery, and parents or legal guardians will be asked to
sign written informed consent for participation in the study. Exclusion criteria will be:
confirmed propofol allergies, mitochondrial disease, disease of lipid and carbohydrate
metabolism, neurological disorders, treated psychiatric comorbidities, hypertension.
All participants will be randomly assigned to two groups: one in which manually controlled
propofol infusion will be used (MC group) and the other with target controlled infusion (TC
group). After anesthesia induction depth of anesthesia during surgery will be measured using
bispectral index (BIS), continuously. As a part of routine monitoring noninvasive blood
pressure monitoring will be measured, and recorded in three time points, as well as heart
rate. Time will be measured from the moment when propofol infusion was stopped till tracheal
extubating.